METHODS FOR DETERMINING DRUG EFFICACY USING IKZF3 (AIOLOS)

Provided herein is use of cereblon-associated protein IKZF3 (Aiolos) as a biomarker to indicate the efficacy of a compound to alter immune response in a subject, and to assess the efficacy of a compound in treating a cancer or an inflammatory disease.

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Bibliographische Detailangaben
Hauptverfasser:	Wang, Maria Yinglin, Corral, Laura, Schafer, Peter H, Lopez-Girona, Antonia, Chopra, Rajesh, Jackson, Pilgrim
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	Provided herein is use of cereblon-associated protein IKZF3 (Aiolos) as a biomarker to indicate the efficacy of a compound to alter immune response in a subject, and to assess the efficacy of a compound in treating a cancer or an inflammatory disease.