PYRIMIDINE COMPOUND, CHLORIDE SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME

The present invention relates to a pyrimidine compound, a chloride salt thereof, and a manufacturing and application of same. The chloride salt of the pyrimidine compound is presented by formula (II). The chloride salt has higher solubility, good stability, higher bioavailability, and very low hygro...

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Bibliographische Detailangaben
Hauptverfasser: ZHANG, Yuanwei, JIN, Fang, CAI, Weihui
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a pyrimidine compound, a chloride salt thereof, and a manufacturing and application of same. The chloride salt of the pyrimidine compound is presented by formula (II). The chloride salt has higher solubility, good stability, higher bioavailability, and very low hygroscopicity, and has excellent inhibition against a PIM kinase.