IMPROVEMENTS IN PREPARATION OF INFLUENZA VIRUS VACCINE ANTIGENS

A number of improvements for preparing vaccine antigens from disintegrated influenza viruses are disclosed. A splitting step can be followed by detergent exchange. Splitting can take place in the presence of a buffer with a higher ionic strength and/or in the presence of phosphate buffer.

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Bibliographische Detailangaben
Hauptverfasser: Haussmann, Christoph, Hauschild, Frank, Jobst, Bjoern
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A number of improvements for preparing vaccine antigens from disintegrated influenza viruses are disclosed. A splitting step can be followed by detergent exchange. Splitting can take place in the presence of a buffer with a higher ionic strength and/or in the presence of phosphate buffer.