SYSTEMS AND METHODS FOR STERILIZING SEALED RADIONUCLIDE GENERATOR COLUMN ASSEMBLIES

Systems and methods for sterilizing a column assembly including a column having an interior containing a retaining media and a parent radionuclide retained by the retaining media, an inlet port in fluid communication with the interior of the column, and an outlet port in fluid communication with the...

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Hauptverfasser: WEHMER, Gregory P, SPETH, Andrew D, SPINELLI, Mark A. Sr, PETROFSKY, Bryan S
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Systems and methods for sterilizing a column assembly including a column having an interior containing a retaining media and a parent radionuclide retained by the retaining media, an inlet port in fluid communication with the interior of the column, and an outlet port in fluid communication with the interior of the column. The method includes sealing at least one of the inlet port and the outlet port to form a sealed column assembly such that fluid communication with the column interior though both the inlet port and the outlet port is prevented, and sterilizing the sealed column assembly to form a terminally-sterilized column assembly.