FORMULATIONS FOR USE IN THE TREATMENT OR IN THE PREVENTION OF UROLOGICAL DISEASES

The present invention concerns a combination of β-sitosterol, oligomeric proanthocyanidins, curcumin having anti -inflammatory and antiproliferative activity for use in the treatment of urological disorders and formulations thereof in combination with suitable excipients and/or diluents. Formulation...

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Bibliographische Detailangaben
Hauptverfasser: SAMARITANI, Giuseppe, CASTELLI, Simone, COSENTINO, Vincenzo
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention concerns a combination of β-sitosterol, oligomeric proanthocyanidins, curcumin having anti -inflammatory and antiproliferative activity for use in the treatment of urological disorders and formulations thereof in combination with suitable excipients and/or diluents. Formulations for oral use associated with at least a promoter of enteric absorption selected among bromelain, L-arginine base, at least one ester of sucrose with fatty acids and pipeline, in particular in the form of a food supplement or medicament, are particularly effective as they exert a significant anti -inflammatory activity and reduce the prostatic volume at dosages of single active ingredients that are much lower than those described in the literature. This effectiveness is due to a mechanism for the promotion of enteric absorption not previously described, original and not explainable as the sum of the actions of the single promoters.