METHOD AND DEVICE FOR MONITORING THE TEMPERATURE OF A CRYOPRESERVED BIOLOGICAL SAMPLE

The invention relates to a device for monitoring the temperature of a cryopreserved biological sample, comprising a sample container (1) having a receiving space (2) for receiving a biological sample (6) and a cover (3) for closing the receiving space. The device also comprises a chamber arranged in...

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Bibliographische Detailangaben
Hauptverfasser: FUHR, Günter R, ZIMMERMANN, Heiko
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to a device for monitoring the temperature of a cryopreserved biological sample, comprising a sample container (1) having a receiving space (2) for receiving a biological sample (6) and a cover (3) for closing the receiving space. The device also comprises a chamber arranged inside the sample container, in particular in the receiving space and/or in the cover, the interior (12; 22; 32; 42) of which is not fluidically connected to the receiving space (2) and is only partially filled with at least one indicator substance (7) having a melting temperature in the region between −20° C. and −140 ° C. The invention also relates to a method for monitoring the temperature of cryopreserved samples, comprising the following steps: providing a device (10; 20; 30; 40) for 12b temperature monitoring; freezing the indicator sub stance/s, wherein the at least one chamber can be placed in a first position during the freezing of the indicator substance/s and in a second position after the freezing and when a temperature of the indicator substance/s is below the melting temperature, in which position a melting of the indicator substance/s leads to an at least partial shift and/or change in shape of the chamber filling, with the influence of the force of gravity.