MICRONEEDLE USING BIODEGRADABLE METAL

The present invention relates to an apparatus for delivering a drug to a body and, more specifically, to a microneedle using a biodegradable metal and to a microneedle patch comprising the same. The microneedle is represented by chemical formula 1, and is absorbed and degraded after the subcutaneous...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KIM, Jong Tack, CHOO, Hyun Wook, CHO, Sung Youn
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to an apparatus for delivering a drug to a body and, more specifically, to a microneedle using a biodegradable metal and to a microneedle patch comprising the same. The microneedle is represented by chemical formula 1, and is absorbed and degraded after the subcutaneous or epithelial insertion to release metal ions and degraded products in the body. In chemical formula 1, a, b, and c represent weight percents of respective ingredients; a + b + c = 100 wt%; and a or b has the highest value in the ranges of 0 ‰¤ a ‰¤ 100, 0 ‰¤ b ‰¤ 100, and 0 ‰¤ c ‰¤ 10; and X is at least one selected from the group consisting of Ca, Fe, Mn, Si, Na, Zr, Ce, and P. The microneedle using a biodegradable metal of the present invention can realize sufficient strength to penetrate the skin due to unique mechanical characteristics of a metal. In addition, the microneedle is subcutaneously inserted to deliver a drug, and then provides the skin with degraded products and gas generated at the time of degradation as well as intrinsic minerals thereof, thereby allowing the skin to swell to ameliorate wrinkles. Therefore, the microneedle can be utilized for drug delivery for therapy, disease prevention through vaccine delivery, drug delivery for skin care, and the like.