LLT-1 ANTIBODIES WITH NEW FUNCTIONAL PROPERTIES

LLT-1 ANTIBODIES WITH NEW FUNCTIONAL PROPERTIES

The present invention relates to monoclonal antibodies that are capable of specifically binding to lectin-like transcript 1 (LLT1), to polynucleotides encoding such antibodies and to cells that express such antibodies. Antibodies of the invention have utility in the treatment of autoimmune diseases...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FRIEDRICHSEN, Birgitte, ZAHN, Stefan, WAGTMANN, Peter Andreas Nicolai Reumert, GALSGAARD, Elisabeth D, BRAUD, Véronique, SPEE, Petrus Johannes Louis
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to monoclonal antibodies that are capable of specifically binding to lectin-like transcript 1 (LLT1), to polynucleotides encoding such antibodies and to cells that express such antibodies. Antibodies of the invention have utility in the treatment of autoimmune diseases and cancer, in which LLT1- and CD161- expressing cells play a role in disease pathogenesis.