METHODS AND SYSTEMS FOR METABOLITE AND/OR LIPID-BASED DETECTION OF COLORECTAL CANCER AND/OR ADENOMATOUS POLYPS

METHODS AND SYSTEMS FOR METABOLITE AND/OR LIPID-BASED DETECTION OF COLORECTAL CANCER AND/OR ADENOMATOUS POLYPS

Described herein are sets of metabolite and lipid (e.g., fatty acid) markers that can be used in the detection of early stage colorectal cancer and/or early development of adenomatous polyps. Presented herein are illustrative pathology-linked panels. In certain embodiments, the markers presented her...

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Hauptverfasser: SÁNCHEZ BROTONS, Alejandro, ADSUAR GÓMEZ, Antonio Jesús, MARTÍNEZ - BAREA, Juan, KRUUSMAA, Kristi, HENSE, Christian, CASADO AGRELO, Jorge, HURTADO CASTILLO, Paola, FABREGAT ROSSELL, Andreu, PAVÓN SOLÍS, Cristina, PERALBO MOLINA, Ángela, ARGAMASILLA MARTÍNEZ, Rosa, BITENC, Marko, DELGADO SÁNCHEZ, Rosa María, JIMÉNEZ GIRÓN, Ana María, RODRÍGUEZ GÓMEZ, Patricia
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Zusammenfassung:Described herein are sets of metabolite and lipid (e.g., fatty acid) markers that can be used in the detection of early stage colorectal cancer and/or early development of adenomatous polyps. Presented herein are illustrative pathology-linked panels. In certain embodiments, the markers presented herein (or subsets thereof) are used as a panel for detecting either colorectal cancer or adenomatous polyps at the same time. The markers presented herein include metabolites and lipids (e.g., fatty acid) freely detectable and accurately quantifiable in human serum. In certain embodiments, the sample may be plasma, urine, saliva, whole blood, dried blood spot or dried serum spot.