ONCOFETAL FIBRONECTIN DETECTION METHOD USING SIMPLE IMMUNOASSAY
The present invention addresses the problem of making it possible, in a simple immunoassay, to prevent false-positive reactions and reduce measurement value errors so as to accurately detect fFN by suppressing a cross-reaction with plasma FN that is an antigenic component similar to fFN to reduce th...
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| Format: | Patent |
| Sprache: | eng ; fre ; ger |
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| Zusammenfassung: | The present invention addresses the problem of making it possible, in a simple immunoassay, to prevent false-positive reactions and reduce measurement value errors so as to accurately detect fFN by suppressing a cross-reaction with plasma FN that is an antigenic component similar to fFN to reduce the detection of plasma FN. When an anti-fFN antibody reacts with fFN in the presence of a specific surfactant according to the present invention, it is possible to accurately detect fFN through the suppression of the cross-reaction between the antibody and FN, even when other FNs such as plasma FN are also present. The specific surfactant is represented by general formula (1):
R-O-(CH 2 CH 2 O) m H(1)
In the formula, m is 4-30, and R represents an alkyl group. |
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