HSP90 INHIBITOR DRUG CONJUGATES

HSP90 INHIBITOR DRUG CONJUGATES

The application concerns an Hsp90 drug conjugate (HDC) comprising an Hsp90 ligand or prodrug thereof, a linker moiety and a payload moiety, wherein the payload moiety is an ERK kinase inhibitor.

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Bibliographische Detailangaben
Hauptverfasser: KOSTIK, Elena, ZHANG, Junyi, VUTUKURI, Dharma, YING, Weiwen, CHIMMANAMADA, Dinesh U
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The application concerns an Hsp90 drug conjugate (HDC) comprising an Hsp90 ligand or prodrug thereof, a linker moiety and a payload moiety, wherein the payload moiety is an ERK kinase inhibitor.