IMPROVED PROCESS FOR THE PREPARATION OF CHIRAL 3-AMINO-PIPERIDINS, USEFUL INTERMEDIATES FOR THE PREPARATION OF TOFACITINIB

IMPROVED PROCESS FOR THE PREPARATION OF CHIRAL 3-AMINO-PIPERIDINS, USEFUL INTERMEDIATES FOR THE PREPARATION OF TOFACITINIB

Object of the present invention is an improved process for the preparation of (3 R ,4 R -1-benzyl-4-methylpiperidin-3-amine by means of chiral Rhodium catalysts.

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Bibliographische Detailangaben
Hauptverfasser: Miserazzi, Emanuele, Preciado Gallego, Sara, Pastó Aguilà, Mireia
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Object of the present invention is an improved process for the preparation of (3 R ,4 R -1-benzyl-4-methylpiperidin-3-amine by means of chiral Rhodium catalysts.