PLATINUM(II) RING-FUSED CHLORINS, METHODS AND USES THEREOF

The present disclosure relates derivatives of platinum (II) ring-fused chlorins with a general formula I or II, more particularly derivatives, which are novel and stable near infrared luminescent compounds for imaging, sensing, optoelectronics applications and use in medicine or as a medicament. (Fo...

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Hauptverfasser: VASCONCELOS DIAS DE PINHO E MELO, Teresa Margarida, MARQUES MARTELO, Liliana, FERREIRA PITA BATISTA PINA, João Manuel, PIÑERO GÓMEZ, Marta, DOUGLAS BURROWS, Hugh, COELHO ABRANTES, Ana Margarida, MELO PEREIRA, Nelson António, RABAÇA ROQUE BOTELHO, Maria Filomena, COIMBRA SERRA, Arménio, LARANJO, Mafalda, SEIXAS DE MELO, João Sérgio
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure relates derivatives of platinum (II) ring-fused chlorins with a general formula I or II, more particularly derivatives, which are novel and stable near infrared luminescent compounds for imaging, sensing, optoelectronics applications and use in medicine or as a medicament. (Formula I and Formula II) (I) (II) This disclosure describes a series of novel, stable near infrared luminescent compounds based on platinum (II) ring-fused chlorins with the general formula I or II. This, coupled with excellent thermal and photochemical stability, makes them excellent materials for use in biological imaging, oxygen sensing and as emitting materials in optoelectronic applications, such as organic light emitting diodes (OLEDs) or bulk heterojunction photovoltaic cells. In addition, their chemical properties allow them to be chemically attached to specific biologically relevant molecules for targeted applications in imaging and theranostics.