A UNIQUE HIGH-SHEAR GRANULATION PROCESS FOR IMPROVED BIOAVAILABILITY OF RIVAROXABAN

A UNIQUE HIGH-SHEAR GRANULATION PROCESS FOR IMPROVED BIOAVAILABILITY OF RIVAROXABAN

Method for preparing granules of rivaroxaban together with pharmaceutically acceptable excipients using high-shear mixing. The granules produced by the methods disclosed herein may be incorporated into dosage forms for oral administration having enhanced oral bioavailability of rivaroxaban.

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Bibliographische Detailangaben
Hauptverfasser: LI, Boyong, REYNOLDS, Thomas, Daniel
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Method for preparing granules of rivaroxaban together with pharmaceutically acceptable excipients using high-shear mixing. The granules produced by the methods disclosed herein may be incorporated into dosage forms for oral administration having enhanced oral bioavailability of rivaroxaban.