ENZYMATIC METHOD FOR PRODUCING 2-HYDROXY-4-METHYLMERCAPTOBUTANOIC ACID (MHA)

The invention relates to an enzymatic method for producing 2-hydroxy-4-methylmercaptobutanoic acid (HMBA, MHA) from 3-methylthio-propanal (3-methylmercaptopropanal (MMP) or "methional") and carbon dioxide using a decarboxylase (EC 4.1.1), its corresponding cofactor, an alcohol dehydrogenas...

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Bibliographische Detailangaben
Hauptverfasser:	Jakob, Harald, Fischer, Daniel, Martin, Julia, Skerra, Arne
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to an enzymatic method for producing 2-hydroxy-4-methylmercaptobutanoic acid (HMBA, MHA) from 3-methylthio-propanal (3-methylmercaptopropanal (MMP) or "methional") and carbon dioxide using a decarboxylase (EC 4.1.1), its corresponding cofactor, an alcohol dehydrogenase (EC 1.1.1) and NADH or NADPH.