PROFILING PEPTIDES AND METHODS FOR SENSITIVITY PROFILING

The present disclosure is generally directed to profiling peptides, compositions, and kits, as well as methods of use thereof. The profiling peptides comprise an Mcl-1 binding domain, and optionally a cellular uptake moiety. The methods of using such profiling peptides include predicting sensitivity...

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Bibliographische Detailangaben
Hauptverfasser: PETERSON, Peter, W, MOURITSEN, Lars, WHATCOTT, Clifford, J, SIDDIQUI-JAIN, Adam, BEARSS, David, J, WARNER, Steven, L
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure is generally directed to profiling peptides, compositions, and kits, as well as methods of use thereof. The profiling peptides comprise an Mcl-1 binding domain, and optionally a cellular uptake moiety. The methods of using such profiling peptides include predicting sensitivity of a cancer, selecting a treatment, treating a cancer, producing a sensitivity profile, and the like.