METHOD FOR ENRICHING A PREPARATION OF IMMUNOGLOBULINS WITH ANTI-RSV IMMUNOGLOBULINS AND PREPARATION ENRICHED IN THIS WAY

METHOD FOR ENRICHING A PREPARATION OF IMMUNOGLOBULINS WITH ANTI-RSV IMMUNOGLOBULINS AND PREPARATION ENRICHED IN THIS WAY

Disclosed is a method for preparing an immunoglobulin (Ig) concentrate useful for treating RSV infection, including a step consisting in subjecting an Ig composition derived from blood plasma to affinity chromatography utilizing an RSV-specific ligand. In a particular embodiment, the RSV-specific li...

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Bibliographische Detailangaben
Hauptverfasser: PERRET, Gérald, CHTOUROU, Abdessatar
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed is a method for preparing an immunoglobulin (Ig) concentrate useful for treating RSV infection, including a step consisting in subjecting an Ig composition derived from blood plasma to affinity chromatography utilizing an RSV-specific ligand. In a particular embodiment, the RSV-specific ligand is an RSV F protein, preferentially in prefusion conformation, or a variant or an antigenic fragment thereof.