RECOMBINANT IMMUNOGLOBULIN HEAVY CHAINS COMPRISING A SORTASE CONJUGATION LOOP AND CONJUGATES THEREOF

The disclosure describes a recombinant immunoglobulin heavy chain comprising a sortase conjugation loop, methods for conjugating and/or labeling such recombinant immunoglobulin heavy chains by use of the enzyme sortase and to the conjugates/labeled products obtained via the method.

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Bibliographische Detailangaben
Hauptverfasser: KUBALEC, Pavel, OELSCHLAEGEL, Tobias, NICHTL, Alfons, ENGEL, Alfred, SCHLECHT, Rainer
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The disclosure describes a recombinant immunoglobulin heavy chain comprising a sortase conjugation loop, methods for conjugating and/or labeling such recombinant immunoglobulin heavy chains by use of the enzyme sortase and to the conjugates/labeled products obtained via the method.