CONDENSED TRICYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

wherein R1, R2, R3 R4, R5, R6, R7a and R7b have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. CDK8 and/or Haspin kinase) is d...

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Bibliographische Detailangaben
Hauptverfasser:	PASTOR FERNÁNDEZ, Joaquín, BLANCO-APARICIO, Carmen, GÓMEZ DE LA OLIVA, Cristina Ana, RIESCO FAGUNDO, Rosario Concepción, RIVERO BUCETA, Virginia, MARTÍNEZ GONZÁLEZ, Sonia, HERNÁNDEZ HIGUERAS, Ana Isabel
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	wherein R1, R2, R3 R4, R5, R6, R7a and R7b have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. CDK8 and/or Haspin kinase) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.