HEAT-STABLE HUMAN EPIDERMAL GROWTH FACTOR-SPIDER VENOM FUSION PROTEIN HAVING IMPROVED SKIN CELL PROLIFERATIVE EFFECT, AND COSMETIC COMPOSITION FOR ALLEVIATING SKIN WRINKLES AND MAINTAINING ELASTICITY, CONTAINING SAME AS ACTIVE INGREDIENT
The present invention relates to a thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect which consists of the amino acid sequence of SEQ ID NO: 2, a gene consisting of E. coli ( Escherichia coli ) codon-optimized nucleotide sequence of...
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| creator | CHOI, Jong Nam KWON, Hyeong Il RYU, Han Bong LEE, Seong Ran CHOI, Tae Won LEE, Sun Kyo KIM, Tae Hyun JEONG, Tae Hwa |
| description | The present invention relates to a thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect which consists of the amino acid sequence of SEQ ID NO: 2, a gene consisting of E. coli ( Escherichia coli ) codon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the aforementioned human epidermal growth factor-spider venom fusion protein, a recombinant vector comprising the aforementioned gene, a host cell transformed with the aforementioned recombinant vector, and a method for producing in a host cell a human epidermal growth factor-spider venom fusion protein by transforming a host cell with the aforementioned recombinant vector, and a cosmetic composition for improving skin wrinkle and maintaining skin elasticity comprising, as an effective component, a human epidermal growth factor-spider venom fusion protein, and as the cosmetic composition of the present invention has excellent thermostability and has an effect of enhancing the activity of improving skin wrinkle and maintaining skin elasticity, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery. |
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INGREDIENT</title><source>esp@cenet</source><creator>CHOI, Jong Nam ; KWON, Hyeong Il ; RYU, Han Bong ; LEE, Seong Ran ; CHOI, Tae Won ; LEE, Sun Kyo ; KIM, Tae Hyun ; JEONG, Tae Hwa</creator><creatorcontrib>CHOI, Jong Nam ; KWON, Hyeong Il ; RYU, Han Bong ; LEE, Seong Ran ; CHOI, Tae Won ; LEE, Sun Kyo ; KIM, Tae Hyun ; JEONG, Tae Hwa</creatorcontrib><description>The present invention relates to a thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect which consists of the amino acid sequence of SEQ ID NO: 2, a gene consisting of E. coli ( Escherichia coli ) codon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the aforementioned human epidermal growth factor-spider venom fusion protein, a recombinant vector comprising the aforementioned gene, a host cell transformed with the aforementioned recombinant vector, and a method for producing in a host cell a human epidermal growth factor-spider venom fusion protein by transforming a host cell with the aforementioned recombinant vector, and a cosmetic composition for improving skin wrinkle and maintaining skin elasticity comprising, as an effective component, a human epidermal growth factor-spider venom fusion protein, and as the cosmetic composition of the present invention has excellent thermostability and has an effect of enhancing the activity of improving skin wrinkle and maintaining skin elasticity, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery.</description><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC USE OF 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Ran</creatorcontrib><creatorcontrib>CHOI, Tae Won</creatorcontrib><creatorcontrib>LEE, Sun Kyo</creatorcontrib><creatorcontrib>KIM, Tae Hyun</creatorcontrib><creatorcontrib>JEONG, Tae Hwa</creatorcontrib><title>HEAT-STABLE HUMAN EPIDERMAL GROWTH FACTOR-SPIDER VENOM FUSION PROTEIN HAVING IMPROVED SKIN CELL PROLIFERATIVE EFFECT, AND COSMETIC COMPOSITION FOR ALLEVIATING SKIN WRINKLES AND MAINTAINING ELASTICITY, CONTAINING SAME AS ACTIVE INGREDIENT</title><description>The present invention relates to a thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect which consists of the amino acid sequence of SEQ ID NO: 2, a gene consisting of E. coli ( Escherichia coli ) codon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the aforementioned human epidermal growth factor-spider venom fusion protein, a recombinant vector comprising the aforementioned gene, a host cell transformed with the aforementioned recombinant vector, and a method for producing in a host cell a human epidermal growth factor-spider venom fusion protein by transforming a host cell with the aforementioned recombinant vector, and a cosmetic composition for improving skin wrinkle and maintaining skin elasticity comprising, as an effective component, a human epidermal growth factor-spider venom fusion protein, and as the cosmetic composition of the present invention has excellent thermostability and has an effect of enhancing the activity of improving skin wrinkle and maintaining skin elasticity, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY 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FACTOR-SPIDER VENOM FUSION PROTEIN HAVING IMPROVED SKIN CELL PROLIFERATIVE EFFECT, AND COSMETIC COMPOSITION FOR ALLEVIATING SKIN WRINKLES AND MAINTAINING ELASTICITY, CONTAINING SAME AS ACTIVE INGREDIENT</title><author>CHOI, Jong Nam ; KWON, Hyeong Il ; RYU, Han Bong ; LEE, Seong Ran ; CHOI, Tae Won ; LEE, Sun Kyo ; KIM, Tae Hyun ; JEONG, Tae Hwa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3339319B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2019</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>CHOI, Jong Nam</creatorcontrib><creatorcontrib>KWON, Hyeong Il</creatorcontrib><creatorcontrib>RYU, Han Bong</creatorcontrib><creatorcontrib>LEE, Seong Ran</creatorcontrib><creatorcontrib>CHOI, Tae Won</creatorcontrib><creatorcontrib>LEE, Sun Kyo</creatorcontrib><creatorcontrib>KIM, Tae Hyun</creatorcontrib><creatorcontrib>JEONG, Tae Hwa</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHOI, Jong Nam</au><au>KWON, Hyeong Il</au><au>RYU, Han Bong</au><au>LEE, Seong Ran</au><au>CHOI, Tae Won</au><au>LEE, Sun Kyo</au><au>KIM, Tae Hyun</au><au>JEONG, Tae Hwa</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HEAT-STABLE HUMAN EPIDERMAL GROWTH FACTOR-SPIDER VENOM FUSION PROTEIN HAVING IMPROVED SKIN CELL PROLIFERATIVE EFFECT, AND COSMETIC COMPOSITION FOR ALLEVIATING SKIN WRINKLES AND MAINTAINING ELASTICITY, CONTAINING SAME AS ACTIVE INGREDIENT</title><date>2019-10-16</date><risdate>2019</risdate><abstract>The present invention relates to a thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect which consists of the amino acid sequence of SEQ ID NO: 2, a gene consisting of E. coli ( Escherichia coli ) codon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the aforementioned human epidermal growth factor-spider venom fusion protein, a recombinant vector comprising the aforementioned gene, a host cell transformed with the aforementioned recombinant vector, and a method for producing in a host cell a human epidermal growth factor-spider venom fusion protein by transforming a host cell with the aforementioned recombinant vector, and a cosmetic composition for improving skin wrinkle and maintaining skin elasticity comprising, as an effective component, a human epidermal growth factor-spider venom fusion protein, and as the cosmetic composition of the present invention has excellent thermostability and has an effect of enhancing the activity of improving skin wrinkle and maintaining skin elasticity, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS SPIRITS VINEGAR WINE |
| title | HEAT-STABLE HUMAN EPIDERMAL GROWTH FACTOR-SPIDER VENOM FUSION PROTEIN HAVING IMPROVED SKIN CELL PROLIFERATIVE EFFECT, AND COSMETIC COMPOSITION FOR ALLEVIATING SKIN WRINKLES AND MAINTAINING ELASTICITY, CONTAINING SAME AS ACTIVE INGREDIENT |
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