GITRL FUSION PROTEINS AND USES THEREOF

The disclosure provides GITRL fusion polypeptide subunits comprising an IgG Fc domain, a trimerization domain, and the receptor binding domain of GITR ligand, where the fusion polypeptide subunits can self-assemble into hexameric proteins. Also provided are methods of making fusion polypeptide subun...

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Bibliographische Detailangaben

Hauptverfasser:	YOUNG, Lesley, Lynn, SRIDHARAN, Sudharsan, LEYLAND, Rebecca, STEWART, Ross, Anthony, BAMBER, Lisa, TIGUE, Natalie, Jo, HIGAZI, Daniel, Ramsay, DURHAM, Nicholas, Mason
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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