HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY

The present invention provides a compound having a TrkA inhibitory activity or a pharmaceutically acceptable salt thereof. The present invention relates to a compound represented by Formula (I): wherein -L- is -C(=X)-, or the like, -Z- is -NR 5 -, or the like, -Z A - is -NR 5A -, or the like, B is s...

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Bibliographische Detailangaben
Hauptverfasser:	INAGAKI, Masanao, NAKAMURA, Kenichiroh, FUJIU, Motohiro, YUKIMASA, Akira, YAMAGUCHI, Hiroki, HATA, Kayoko, INOUE, Takatsugu, KANO, Kazuya
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound having a TrkA inhibitory activity or a pharmaceutically acceptable salt thereof. The present invention relates to a compound represented by Formula (I): wherein -L- is -C(=X)-, or the like, -Z- is -NR 5 -, or the like, -Z A - is -NR 5A -, or the like, B is substituted or unsubstituted aromatic carbocyclyl, or the like, Y is a single bond, or the like, the ring C is a substituted or unsubstituted aromatic heterocycle, or the like, R 2 is a hydrogen atom, or the like, and the group represented by is a group represented by Formula: or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.