CAPTURE PROBES IMMOBILIZABLE VIA L-NUCLEOTIDE TAIL

CAPTURE PROBES IMMOBILIZABLE VIA L-NUCLEOTIDE TAIL

There is disclosed a method of capturing a target nucleic acid, comprising: contacting a target nucleic acid with a capture probe and an immobilized probe, the capture probe comprising a first segment that binds to the target nucleic acid and a second segment that binds to the immobilized probe, whe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MAJLESSI, Mehrdad, ARNOLD, Lyle J Jr, REYNOLDS, Mark, YAMAGATA, Susan, BECKER, Michael M, POLLNER, Reinhold B
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:There is disclosed a method of capturing a target nucleic acid, comprising: contacting a target nucleic acid with a capture probe and an immobilized probe, the capture probe comprising a first segment that binds to the target nucleic acid and a second segment that binds to the immobilized probe, wherein the second segment of the capture probe and the immobilized probe comprise L-nucleic acids that can hybridize to one another, wherein the target nucleic acid binds to the first segment of the capture probe, and the second segment of the capture probe binds to the target, thereby capturing the target nucleic acid.