CRYSTAL FORMS OF TETRA-HYDRO-N, N-DIMETHYL-2, 2-DIPHENYL-3-FURANMETHANAMINE HYDROCHLORIDE, PROCESSES FOR MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS

CRYSTAL FORMS OF TETRA-HYDRO-N, N-DIMETHYL-2, 2-DIPHENYL-3-FURANMETHANAMINE HYDROCHLORIDE, PROCESSES FOR MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS

Polymorphic forms of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (ANAVEX2-73) and a metabolite of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (ANAVEX19-144) are disclosed and characterized. Compositions and method for treatment of Alzheimer's...

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Bibliographische Detailangaben
Hauptverfasser: LEONARD, Lucy, Anne, DAINTREE, Linda, Sharon, YORK, Peter, LEDGER, Daniel, Mark
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Polymorphic forms of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (ANAVEX2-73) and a metabolite of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (ANAVEX19-144) are disclosed and characterized. Compositions and method for treatment of Alzheimer's disease that includes the polymorphic forms and metabolite of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (ANAVEX2-73).