BICYCLIC HETEROCYCLES AS INHIBITORS OF CHOLESTEROL ESTER TRANSFER PROTEIN

The invention provides compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein D1, D2, D3, X, Y, A1, A2, R1, R5 and the subscript a are as described herein. The compounds are CETP inhibitors and are useful for raising FIDL-cholesterol, reduc...

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Bibliographische Detailangaben
Hauptverfasser: THATAI, Jayanth Thiruvellore, VACHAL, Petr, SHAO, Pengcheng Patrick, SARKAR, Sujit Kumar, KATIPALLY, Revathi Reddy
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention provides compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein D1, D2, D3, X, Y, A1, A2, R1, R5 and the subscript a are as described herein. The compounds are CETP inhibitors and are useful for raising FIDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: