INHALABLE EPINEPHRINE

The present invention is directed toward particles for delivery of epinephrine to the respiratory system and methods for treating a patient in need of epinephrine. The particles and respirable compositions comprising the particles of the present invention described herein comprise the bioactive agen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SUMMA, Jason, CHILDS, Mariko, HRKACH, Jeffrey S, PAN, Mei-Ling, CAPONETTI, Giovanni, KI, Wen-I, BATYCKY, Richard P, LIPP, Michael M, EHRICH, Eliot, FU, Karen
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention is directed toward particles for delivery of epinephrine to the respiratory system and methods for treating a patient in need of epinephrine. The particles and respirable compositions comprising the particles of the present invention described herein comprise the bioactive agent epinephrine, or a salt thereof, as a therapeutic agent. The particles are preferably formed by spray drying. Preferably, the particles and the respirable compositions are substantially dry and are substantially free of propellents. In a preferred embodiment, the particles have aerodynamic characteristics that permit targeted delivery of epinephrine to the site(s) of action.