PROTECTIVE AGENTS AGAINST E-BEAM IRRADIATION FOR PROTEINS IN OPTICAL SENSING CHEMISTRY

Medical devices are typically sterilized in processes used to manufacture such products and their sterilization by exposure to radiation is a common practice. Radiation has a number of advantages over other sterilization processes including a high penetrating ability, relatively low chemical reactiv...

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Bibliographische Detailangaben
Hauptverfasser: AROYAN, Sarkis, KRISTENSEN, Jesper Svenning, DANG, Tri T
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Medical devices are typically sterilized in processes used to manufacture such products and their sterilization by exposure to radiation is a common practice. Radiation has a number of advantages over other sterilization processes including a high penetrating ability, relatively low chemical reactivity, and instantaneous effects without the need to control temperature, pressure, vacuum, or humidity. Unfortunately, radiation sterilization can compromise the function of certain components of medical devices. For example, radiation sterilization can lead to loss of protein activity and/or lead to bleaching of various dye compounds. Embodiments of the invention provide methods and materials that can be used to protect medical devices from unwanted effects of radiation sterilization.