TAXANE PARTICLES AND THEIR USE

Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30...

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Bibliographische Detailangaben
Hauptverfasser: SITTENAUER, Jake, FISCHER, Julia, K, ESPINOSA, Jahna, BALTEZOR, Michael, FARTHING, Joseph, CAMPBELL, Samuel, WILLIAMS, Mark, D, MCCLOREY, Matthew, CLAPP, Gary, E
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.