CANCER VACCINE COMPRISING MRNA ENCODING A M-LIKE-PROTEIN

CANCER VACCINE COMPRISING MRNA ENCODING A M-LIKE-PROTEIN

Synthetic bacterial messenger RNA can be used to prepare autologous, allogenic or direct nucleic acid cancer vaccines. Cancer cells are transfected either in vitro or in vivo with mRNA obtained from DNA that encodes an immunogenic bacterial protein. An immune response to the cancer is generated from...

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Bibliographische Detailangaben
Hauptverfasser: BASTAWROUS, Marina Victor, Abdelmaseeh, LAWMAN, Michael, J.P, RAMIYA, Vijay, LAWMAN, Patricia, D, GENTILINI, Meghan
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Synthetic bacterial messenger RNA can be used to prepare autologous, allogenic or direct nucleic acid cancer vaccines. Cancer cells are transfected either in vitro or in vivo with mRNA obtained from DNA that encodes an immunogenic bacterial protein. An immune response to the cancer is generated from direct administration of the mRNA in vivo or administration of vaccines prepared from cancer cells in vitro.