INDAZOLONES AS MODULATORS OF TNF SIGNALING

INDAZOLONES AS MODULATORS OF TNF SIGNALING

The disclosure provides indazolone compounds, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the disclosure may be useful for treating immunological and oncological conditions...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OSUMA, Augustine, BREINLINGER, Eric, IHLE, David, MULLEN, Kelly, FRIEDMAN, Michael, LO SCHIAVO, Gloria, Y, ARGIRIADI, Maria, MORYTKO, Michael, DIETRICH, Justin, D, WILSON, Noel, S
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The disclosure provides indazolone compounds, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the disclosure may be useful for treating immunological and oncological conditions.