LOW MOLECULAR WEIGHT HALOGENATED PORPHYRINE CARBOXAMIDE CHLORIN AND BACTERIOCHLORIN DERIVATIVES FOR USE IN PHOTODYNAMIC THERAPY FOR TREATING CANCER

The present invention relates to carboxamide halogenated porphyrin derivatives, in particular bacteriochlorin or chlorin, of formula (I) use of the same or a pharmaceutically acceptable salt thereof in photodynamic therapy, where the derivatives are able to detect and exhibit the presence of hyperpr...

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Bibliographische Detailangaben
Hauptverfasser:	SCHABERLE, Fabio Antonio, BORGES ROCHA, Luis Gabriel, FERREIRA GONÇALVES, Nuno Paulo, FERRAZ CARDOSO SOARES, Hélder Tão, MIGUÉNS PEREIRA, Maria, PEREIRA MONTEIRO, Carlos Jorge, REIS DE ABREU, Artur Carlos, DA SILVA ARNAUT MOREIRA, Luis Guilherme, PEREIRA NASCIMENTO COSTA, Gonçalo
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to carboxamide halogenated porphyrin derivatives, in particular bacteriochlorin or chlorin, of formula (I) use of the same or a pharmaceutically acceptable salt thereof in photodynamic therapy, where the derivatives are able to detect and exhibit the presence of hyperproliferative disorders and, in the presence of an adequate lighting, to treat the same. The present invention also describes a pharmaceutical composition having the carboxamide halogenated porphyrin derivatives, in particular bacteria-chlorin or chlorin, of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of cancer and/or microbial and/or viral infections, in humans or animals.