CHOLESTEROL EFFLUX CAPACITY ASSESSMENT

A method is provided for transforming one or more biomarkers into a cholesterol efflux capacity (CEC) level. Methods relate to determining SR-BI-mediated and ABCA1-mediated CEC. CEC may be used for compound screening and to determine risk of cardiovascular disease and to recommend or administer trea...

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Bibliographische Detailangaben
Hauptverfasser: ASZTALOS, Bela, F, SCHAEFER, Ernst, J, RIEL-MEHAN, Michael
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A method is provided for transforming one or more biomarkers into a cholesterol efflux capacity (CEC) level. Methods relate to determining SR-BI-mediated and ABCA1-mediated CEC. CEC may be used for compound screening and to determine risk of cardiovascular disease and to recommend or administer treatment regimens.