ACYLATED 4-AMINOPIPERIDINES AS INHIBITORS OF SERINE PALMITOYLTRANSFERASE

The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).

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Bibliographische Detailangaben
Hauptverfasser: SAITO, Bunnai, KOJIMA, Takuto, IWAMURA, Naoki, MIYAMOTO, Yasufumi, ASANO, Yasutomi, ARAI Ryosuke, YONEMORI, Kazuko, KITAMURA, Shuji, SANO, Osamu, WONG, Tzu-Tshin, KURASAWA, Osamu, IMAMURA, Shinichi, HIRATA, Yasuhiro, TANAKA, Yuta
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).