SET OF POLYPEPTIDES EXHIBITING NUCLEASE ACTIVITY OR NICKASE ACTIVITY WITH DEPENDENCE ON LIGHT OR IN PRESENCE OF DRUG OR SUPPRESSING OR ACTIVATING EXPRESSION OF TARGET GENE

The present invention provides, for example, a set of two polypeptides exhibiting the nuclease activity with dependence on light or in the presence of a drug, in which an N-terminal side fragment and a C-terminal side fragment of a Cas9 protein are bound to each of two polypeptides which form a dime...

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Bibliographische Detailangaben
Hauptverfasser: SATO, Moritoshi, NIHONGAKI, Yuta
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides, for example, a set of two polypeptides exhibiting the nuclease activity with dependence on light or in the presence of a drug, in which an N-terminal side fragment and a C-terminal side fragment of a Cas9 protein are bound to each of two polypeptides which form a dimer with dependence on light or in the presence of a drug.