METHOD FOR PRODUCING EPIRUBICIN AND NOVEL PRODUCTION INTERMEDIATE THEREFOR

METHOD FOR PRODUCING EPIRUBICIN AND NOVEL PRODUCTION INTERMEDIATE THEREFOR

According to the present invention, it is possible to efficiently remove 13-dihydroepi-daunorubicin and 4'-epi-feudomycin, which are typical impurities possibly contained in 4'-epi-daunorubicin as a starting material, by using an organic acid salt of 4'-epi-daunorubicin or a hydrate o...

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Hauptverfasser: MORI Kenichiro, SHIOKAWA Sojiro, UMEZU Takuto, MARUYAMA Takahisa
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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creator MORI Kenichiro
SHIOKAWA Sojiro
UMEZU Takuto
MARUYAMA Takahisa
description According to the present invention, it is possible to efficiently remove 13-dihydroepi-daunorubicin and 4'-epi-feudomycin, which are typical impurities possibly contained in 4'-epi-daunorubicin as a starting material, by using an organic acid salt of 4'-epi-daunorubicin or a hydrate or solvate thereof as a novel production intermediate, thus making it possible to produce high-purity epirubicin.
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subjects CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
title METHOD FOR PRODUCING EPIRUBICIN AND NOVEL PRODUCTION INTERMEDIATE THEREFOR
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