METHOD FOR PRODUCING EPIRUBICIN AND NOVEL PRODUCTION INTERMEDIATE THEREFOR

According to the present invention, it is possible to efficiently remove 13-dihydroepi-daunorubicin and 4'-epi-feudomycin, which are typical impurities possibly contained in 4'-epi-daunorubicin as a starting material, by using an organic acid salt of 4'-epi-daunorubicin or a hydrate o...

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Bibliographische Detailangaben
Hauptverfasser:	MORI Kenichiro, SHIOKAWA Sojiro, UMEZU Takuto, MARUYAMA Takahisa
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS
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Beschreibung
Zusammenfassung:	According to the present invention, it is possible to efficiently remove 13-dihydroepi-daunorubicin and 4'-epi-feudomycin, which are typical impurities possibly contained in 4'-epi-daunorubicin as a starting material, by using an organic acid salt of 4'-epi-daunorubicin or a hydrate or solvate thereof as a novel production intermediate, thus making it possible to produce high-purity epirubicin.