SELECTIVE INHIBITORS OF HEMICHANNELS FORMED BY CONNEXINS FOR THE TREATMENT OF EPILEPSY

The present invention provides connexin hemichannel blockers for the treatment of epilepsy. In particular, the present invention relates to organic compounds which act as selective blockers of connexin hemichannels which are useful in the treatment of epilepsy. In another embodiment of the present i...

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Bibliographische Detailangaben
Hauptverfasser:	MATURANA, Carola, LAGOS, Carlos, SAEZ, Juan Carlos
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides connexin hemichannel blockers for the treatment of epilepsy. In particular, the present invention relates to organic compounds which act as selective blockers of connexin hemichannels which are useful in the treatment of epilepsy. In another embodiment of the present invention it is provided a composition comprising selective connexin hemichannels blocker compounds useful in the treatment of epilepsy in combination with other antiepileptic compounds.