SALTS, PRODRUGS AND POLYMORPHS OF FAB I INHIBITORS

Salts of compounds according to formula (I), wherein X is selected from the group consisting of H 2 SO 4 , HSO 3 R', HSO 3 Ar, H 3 PO 4 , HCl, HBr, CF 3 CO 2 H and CCl 3 CO 2 H, are provided. The preferred salt is the p-toluene sulfonate. These compounds and their pharmaceutical compositions ar...

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Bibliographische Detailangaben
Hauptverfasser:	PAULS, Henry, RAMNAUTH, Jailall
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Salts of compounds according to formula (I), wherein X is selected from the group consisting of H 2 SO 4 , HSO 3 R', HSO 3 Ar, H 3 PO 4 , HCl, HBr, CF 3 CO 2 H and CCl 3 CO 2 H, are provided. The preferred salt is the p-toluene sulfonate. These compounds and their pharmaceutical compositions are useful as Fab1 inhibitors for treating bacterial infections.