PROCESSES FOR PREPARING ASK1 INHIBITORS

PROCESSES FOR PREPARING ASK1 INHIBITORS

The present disclosure provides processes for the preparation of a compound of formula:which exhibits apoptosis signal-regulating kinase ("ASK1") inhibitory activity and is thus useful in the treatment of diseases such as kidney disease, diabetic nephropathy and kidney fibrosis. The disclo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CHIU, Anna, REYNOLDS, Troy Evan, SILER, David Allen, BROWN, Brandon Heath, GRIGGS, Nolan, CHAN, Brenda J. Burke, LATHROP, Stephen P, HEUMANN, Lars V, SARMA, Keshab, THOMPSON, Andrew S, WANG, Tao, NOTTE, Gregory
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present disclosure provides processes for the preparation of a compound of formula:which exhibits apoptosis signal-regulating kinase ("ASK1") inhibitory activity and is thus useful in the treatment of diseases such as kidney disease, diabetic nephropathy and kidney fibrosis. The disclosure also provides compounds that are synthetic intermediates.