ERK INHIBITORS

The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and a pharmaceut...

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Bibliographische Detailangaben
Hauptverfasser:	LIU, Ziping, BOYCE, Christopher, KARUNAKARAN, Ganesh Babu, GUERIN, David, WITTER, David, LIU, Wei, SILIPHAIVANH, Phieng, SLOMAN, David, L, HUANG, Xianhai, LIM, Jongwon, MOLINARI, Danielle, ZHOU, Hua, WAN, Zhilong, BAKSHI, Raman Kumar, METHOT, Joey, FU, Jianmin, LIPFORD, Kathryn Ann
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and a pharmaceutically acceptable carrier. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and an effective amount of at least one other pharmaceutically active ingredient (such as, for example, a chemotherapeutic agent), and a pharmaceutically acceptable carrier.