PEPTIDES FOR TARGETING COLORECTAL CANCER, AND MEDICAL USE THEREOF

The present invention relates to a peptide for targeting colorectal cancer, a composition for diagnosing radioresponsiveness-dependent prognosis of colorectal cancer using the peptide, and a drug delivery use of the peptide. A functional peptide capable of targeting cancer has been discovered so as...

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Bibliographische Detailangaben
Hauptverfasser: CHOI, Eun Kyung, PARK, Jaesook, LEE, Kyoung Jin, PARK, Seok Soon, JEONG, Seong-Yun, LEE, Jae Hee, CHOI, Jinhyang, SONG, Si Yeol
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a peptide for targeting colorectal cancer, a composition for diagnosing radioresponsiveness-dependent prognosis of colorectal cancer using the peptide, and a drug delivery use of the peptide. A functional peptide capable of targeting cancer has been discovered so as to implement personalized diagnosis and treatment for individual patients having cancer, in consideration of problems occurring during treatment in which treatment cases of respective patients differ due to different therapeutic responses resulting from genetic differences in the individual patients. After establishing animal models similar to cancer microenvironments of actual patients and dividing them into an irradiated population and a non-irradiated population as a control group, targeting efficiency has been tested for respective peptides selected by screening peptides specifically binding to the respective populations. As such, the present invention can be finally utilized in the technical development of image diagnosis for predicting responsiveness to radiotherapy, and accordingly, in the development of customized targeted therapeutic agents.