DNA PLASMID, CODING HNP-1, OR HNP-2, OR HNP-3, BACTERIAL PRODUCER, ANALGESIC AGENT (VARIANTS)

The invention (variants) relates to the field of medicine, pharmacology, biotechnology, molecular biology and genetic engineering, and may be used for analgesia. A proposed DNA plasmid for transient expression in mammalian cells, consists of a framework, containing prokaryotic and eukaryotic element...

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Bibliographische Detailangaben
Hauptverfasser:	Orlov, Anton Iosifovich, Dukhovlinov, Ilya Vladimirovich
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention (variants) relates to the field of medicine, pharmacology, biotechnology, molecular biology and genetic engineering, and may be used for analgesia. A proposed DNA plasmid for transient expression in mammalian cells, consists of a framework, containing prokaryotic and eukaryotic elements, and of a polynucleotide, which encodes human alpha defensin HNP-1, or HNP-2, or HNP-3 (variants). Additionally proposed are a producer of such a DNA plasmid, said producer being based on a bacterial cell (variants), and an analgesic agent based thereon for application in mammals, and specifically humans (variants). The technical result from using the variants of the invention is expressed in broadening the spectrum of analgesic agents, in increasing the duration of analgesia, in increasing the safety of analgesia, and in simplifying and reducing the cost of producing an analgesic.