METHOD FOR PRODUCING GAMMA-DELTA T CELLS, AND PHARMACEUTICAL

The purpose of the present invention is to provide a method for producing ³´T cells with which it is possible to obtain a cell population including a large amount of y´T cells and including virtually no cells infected by human T-cell leukemia virus (HTLV) even when PBMCs derived from a person infect...

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Bibliographische Detailangaben
Hauptverfasser:	YAMANO Yoshihisa, MUTO Masato, SEINO Ken-ichiro
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The purpose of the present invention is to provide a method for producing ³´T cells with which it is possible to obtain a cell population including a large amount of y´T cells and including virtually no cells infected by human T-cell leukemia virus (HTLV) even when PBMCs derived from a person infected with HTLV are used as the cell source. A cell population including a large amount of y´T cells and including virtually no HTLV-1-infected cells is obtained by culturing after removing CD4-positive cells that express CD4 (referred to hereinafter as "CD4 + cells") and CD8-positive cells that express CD8 (referred to hereinafter as "CD8 + cells") from the PBMCs that are used as the cell source, or after removing cells that express ±²T cell receptors (±²TCR) (referred to hereinafter as "±²T cells"), before expanding ³´T cells.