INHIBITORS OF HIF PROLYL HYDROXYLASE

The present invention concerns a compound of formula I or a pharmaceutically acceptable salt thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin suc...

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Bibliographische Detailangaben
Hauptverfasser:	DEBENHAM, John, DU, Xiaoxing, COLANDREA, Vincent, GUIADEEN, Deodialsingh, MADSEN-DUGGAN, Cristina, B, WANG, Liping, CRESPO, Alejandro, CAI, Jiaqiang, LIU, Rongqiang, MCCOY, Joshua, G, QUAN, Weiguo, SINZ, Christopher, LIU, Ping
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention concerns a compound of formula I or a pharmaceutically acceptable salt thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.