HUMAN ANTIBODY SPECIFIC TO C-MET AND PREPARATION METHOD THEREFOR

Provided are an antibody specifically bound to c-Met (c-Met-specific antibody) or fragments thereof, and more specifically, a fully human antibody having high affinity and specificity to c-Met isolated from human Fv(ScFv) phage library, a polynucleotide encoding the antibody, a recombinant vector co...

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Hauptverfasser:	LEE, Hyuk Joon, SHIM, Sang Ryeol, CHOI, Jinhee, OH, Seon Hwan, JEONG, Jong Geun, LEE, Eun Hee, YOO, Jinsang, YOON, Jae Bong, YOO, Jin San, NAHM, Kyoung Hee, JEONG, Ji Hye, LEE, Weon Sup, NAM, Ju Ryoung, KIM, Yeon Ju, KIM, Nam Ye, BYUN, Sang Soon, PARK, Miju, KIM, Do Yun, JEON, Mi Ae, KIM, Sung-Woo, JEONG, Boyoung, LEE, Youngae, LEE, Seon Young
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided are an antibody specifically bound to c-Met (c-Met-specific antibody) or fragments thereof, and more specifically, a fully human antibody having high affinity and specificity to c-Met isolated from human Fv(ScFv) phage library, a polynucleotide encoding the antibody, a recombinant vector containing the polynucleotide, a cell transformed with the recombinant vector, and a method of producing the c-Met-specific antibody by culturing the cell, wherein the c-Met-specific antibody may effectively control activity of c-Met in vivo.