MULTI-ELECTRODE BIOSENSOR SYSTEM

An analyte biosensor system (1200), comprising: at least two substrates forming a reservoir (1208), the reservoir including at least one primary area, at least one sample port (1211), at least two vents, and at least a first and a second substantially chemically isolated secondary analysis regions, the first secondary analysis region including at least one first electrode in electrical communication with a first conductor (1290), the second secondary analysis region including at least one second electrode in electrical communication with a second conductor (1290); a sample interface (1214) in electrical communication with the first conductor, the second conductor, and a third conductor in the reservoir; and a sensor interface (1218) in electrical communication with the sample interface; a processor (1222) in electrical communication with the sensor interface (1218), the processor is operable to determine the time when a fluid sample entering the reservoir contacts the first electrode and the time when a fluid sample entering the sample reservoir contacts the second electrode.