COMPOUNDS AND COMPOSITIONS AS RAF KINASE INHIBITORS

The present invention provides compounds of Formula (I) and (II) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and...

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Bibliographische Detailangaben
Hauptverfasser: SENDZIK, Martin, LOU, Yan, RICO, Alice C, SETTI, Lina Quattrocchio, WAN, Lifeng, BURGER, Matthew T, TAFT, Benjamin R, AVERSA, Robert John, RAUNIYAR, Vivek, DINEEN JR., Thomas A, SUBRAMANIAN, Sharadha, DILLON, Michael Patrick, RAMURTHY, Savithri, NISHIGUCHI, Gisele A, TANNER, Huw Rowland
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides compounds of Formula (I) and (II) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.