SUPERSATURATED COMPOSITIONS OF BENZIMIDAZOLE COMPOUNDS

The invention relates to a stable supersaturated aqueous solution comprising a benzimidazole compound of formula (I) and an organic carboxylic acid selected from the group consisting of substituted or unsubstituted aliphatic C 3 -C 8 ±,É-dicarboxylic acids and substituted or unsubstituted aliphatic...

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Bibliographische Detailangaben
Hauptverfasser:	GARCÍA DOMÍNGUEZ, Neftalí, CANAL MORI, Gonzalo, HERNÁNDEZ HERRERO, Gonzalo, RUBIO ROYO, Víctor, TESSON, Nicolas
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a stable supersaturated aqueous solution comprising a benzimidazole compound of formula (I) and an organic carboxylic acid selected from the group consisting of substituted or unsubstituted aliphatic C 3 -C 8 ±,É-dicarboxylic acids and substituted or unsubstituted aliphatic C 2 -C 6 monocarboxylic acids and to its use in the treatment and/or prevention of conditions mediated by H 1 histamine receptor, such as allergic disorders or diseases. The invention also relates to the use of the above organic carboxylic acids to increase the aqueous solubility of benzimidazole compounds of formula (I).