SYNTHETIC SOMATOSTATIN RECEPTOR LIGANDS

Disclosed are Somatostatin receptor ligands comprising a peptide moiety, pharmaceutical compositions and uses thereof. Disclosed are also synthetic Somatostatin receptor ligands comprising a cyclic peptide moiety and an active agent moiety covalently bonded to the cyclic peptide moiety through a nit...

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Bibliographische Detailangaben
Hauptverfasser: SALITRA, Yoseph, GAZIT, Ehud, ORENSTEIN, Arie, SHEKHTER ZAHAVI, Talia, BUZHANSKY, Ludmila, ORON-HERMAN, Mor, KOSTENICH, Genady
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed are Somatostatin receptor ligands comprising a peptide moiety, pharmaceutical compositions and uses thereof. Disclosed are also synthetic Somatostatin receptor ligands comprising a cyclic peptide moiety and an active agent moiety covalently bonded to the cyclic peptide moiety through a nitrogen atom of a side chain functional group of an internal residue of the cyclic peptide moiety, pharmaceutical compositions and uses thereof. Disclosed are also synthetic Somatostatin receptor ligands comprising a cyclic peptide moiety and a nanoparticle active agent moiety covalently bonded to the cyclic peptide moiety, pharmaceutical compositions and uses thereof.