METHOD FOR TREATING PATIENTS HAVING CANCEROUS SKIN DISEASES (VARIANTS)

The invention refers to medicine, in particular to oncology, pharmacology and veterinary science, and can be used for treatment and prevention of neoplastic processes of skin tissues - squamous-cell and basal-cell skin cancer, as well as melanoma and other benignant and malignant skin tumors, with the help of pharmaceutical preparation including protein-polypeptide complex produced from homogenates of nervous and skin tissues of the hoofed livestock. In the claimed invention, protein-polypeptide complex is used as a primary active substance (biologically active substance), it is represented as a biologically active protein-polypeptide complex (hereinafter - PPC) with the molecular mass of its constituent components within the range of 5-200 kDa and content of medium molecular fraction within the range of 10 to 120 kDa in at least 80%, general protein content 0.2 - 4.2 mg/ml, maximum absorption peak of UV spectrum of solution at the wave length 280±5nm, peak presence at the wave length 274-284 nm in the UV-visible spectrum, presence of specific bands within pl range from 4.2 to 8.4 at isoelectric focusing in 5% polyacrilamide gel and pharmaceutically acceptable agent, for example diluents, as well as conventional agents (pharmaceutically acceptable) upon composition of pastes, gels, creams, etc., and the diluents can include buffer solution and excipients - high-molecular compounds belonging to the class of preservatives and solubilizers in sufficient concentrations. The substance is produced by ion-exchange chromatography of filtrate of extracted homogenate of skin, cerebral and spinal cord tissues of hoofed livestock's embryos with the gestation period from the middle of the first third till the middle of the last third in the presence of buffer solution, detergents, proteolysis inhibitors and solubilizers. The method implies use of the specified protein-polypeptide complex both in the form of solutions, suspension in pharmaceutically acceptable carriers, diluents in composition of auxiliary additives, and in the form of pastes, gels, liposomal emulsion, both for treatment and for simultaneous treatment and prevention of oncological skin diseases.